Completed Projects

Medical devices developed at BETiC and licensed to start-up companies, manufacturers or NGOs; given to hospitals for clinical studies, and being taken forward for production and supply are described in this chapter. This includes 16 products in three categories:

  • Diagnosis, screening& monitoring (low-risk devices): smart stethoscope, Clubfoot brace monitor, diabetic foot screener, Endotracheal tube obstruction monitor glaucoma screener, biopsy gun.
  • Surgical instruments & software (low-medium risk): surgery planner, laparoscopy instrument, aortic valve template, nasal osteotomy forceps, surgery guides, skin gun.
  • Prostheses, orthoses &implants (medium-high risk): prosthetic leg, fracture splint, silicone implants, bone scaffold implant, compression screw, cleft palate impression tray.

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Medical products developed at BETiC IITB, VNIT, and COEP

   1. Endotracheal Tube Monitor

The endotracheal tube obstruction monitor device is a non-invasive device, which can be easily connected in between the endotracheal tube, and mechanical ventilator by using specially designed ‘junction connector’. The endotracheal tube gets obstruct due to the internal secretion of the human body and resulting in serious injury to humans or leads to death. This proposed device will help to detect the obstruction that occurs/present in the tube at the early stage. Presently clinicians observe the behavior of a mechanical ventilator to detect the obstruction and most of the time obstruct detection occurs when it reaches to last level.

Clinical Need Definition: Intubation is a regular practice in the intensive care unit, it is not new that the patient has lost their lives due to obstruction occurs in the endotracheal tube. Clinicians are always trying to detect the obstruction in the endotracheal tube using a few traditional methods as discussed above. However, none of them is producing accurate results so it is very difficult to detect obstruction in the endotracheal tube. To put the new endotracheal tube inside the human body through the mouth is also one of the challenging tasks in the intensive care unit and needs a very skilled hand to perform incubation. It is very important to make a device that will detect the endotracheal tube obstruction at early level. This will saves many lives.

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L-R: CAD Model of device, Testing with AMBU bag

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L-R: Discussion with Dr. Kadam and Dr. Sonali Salvi, Device Prototype

Device Development: Dr. Sonali Salvi from B.j Medical and Sassoon General Hospital Pune and Dr. Sandeep Anasane BETiC-COEPmentored this project. Aiming to make a device that will monitor and detect the obstruction present in the endotracheal tube of any size.

Values and Benefits

  1. Continuous Feedback: This device continuously provides information related to endotracheal tube obstruction. Real-Time MonitoringInformation is in real-time to assist clinicians in better monitoring their patients.
  2. Actionable Information: This device provides detailed information regarding endotracheal obstruction to clinicians to improve the care of intubated patients.
  3. Easy to Use and low cost: This device will have, easy-to-use interface displays, graphics, alarm configurations, wireless communication with other system and user instructions help clinicians easily learns how to use the proposed device.
  4. Compact and Complete: This device is a small handheld, portable device which will work with all major mechanical ventilation systems and any brand of the endotracheal tube.
  5. Potential Improvement in Quality of Care: Preliminary experiments demonstrate efficacy in providing direct, precise, real-time monitoring of endotracheal tube obstructions, which may also result in improved patient safety and quality of care.

Mr. Abhijeet Bhagat, who is involved in this project right from the inception of this device, the device has won the Biotechnology Ignition Grant (BIG) of Rs.50.00 Lakh for the startup. Recently he has registered Atmen Technovention Pvt. Ltd., health care device domain startup.

 

 2. Skin Gun

In India, over one million people get burnt every year. The most common treatment for severe burns is by grafting skin tissue taken from another area of the patient’s body. The procedure is painful, prone to complications and slow-to-heal. There is a need for better utilization of tissue taken from the donor sites and reduce hospitalization time of patients.

Clinical Need Definition: For patients with major burns, who have limited donor site area, an epidermal spray or skin gun is used. A small strip of skin is harvested, minced, added to saline fluid and sprayed over the burn area. The skin pieces act as seeds for new skin to grow and cover the wound area. In consultation with Dr. Nikhil Panse and Dr. Rohit Phulwar, B.J. Medical College, BETiC-COEP researchers Saiprasad Poyarekar and Chetan Mahale guided by Dr. Sandeep Anasane and Prof.B.B. Ahuja defined the need as “hand-driven spray gun for controlled uniform distribution of skin tissue pieces”.

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Left- Skin graft and spraying. Right- the Proposed concept of device

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Left- Prototype device with electronics. Right- Dr. Nikhil Panse with BETiC-COEP team

Device Development: The proof-of-concept used a controlled flow of compressed air mixed with a solution containing skin minced graft cells and released on burn areas. The proof-of-concept was tested with pieces of paper, glitter plastic, and chicken skin and achieved a 1:15 expansion ratio. There were difficulties in spraying skin over large burn area due to its stickiness and own weight. An easily detachable and autoclavable stirrer mechanism was designed to maintain a uniform solution of skin pieces and saline. The flow of skin is controlled by electronics systems. The team is working on a light-weight functional prototype with electronically controlled valves to provide the desired specificity and sensitivity. Pre-clinical trials and clinical trials are planned at B.J. Medical College, Pune.

Mr. Saiprasad Poyarekar, who is involved in this project right from the inception of this device, the device has won the Biotechnology Ignition Grant (BIG) of Rs.50.00 Lakh for the startup. Recently he started Pacify Medical Technologies Pvt. Ltd., health care device domain startup.